5-MeO-DMT - The Psychoactive Experience That’s Transforming Lives

When you're seeking out a psychoactive experience, you're often searching for a part of yourself that seems to be missing, to comprehend things about yourself that you don't understand. You want to unlock your true potential.Enlightenment is a path that eludes many. 5-MeO-DMT could be a catalyst for your journey. Many of those who have worked with the medicine have reported that their trip was an earth-shattering event, one that completely altered their mental paradigm.That said, we are hardly suggesting that 5-MeO-DMT is some magical medicine that makes your life better the moment you take it. At Tandava Retreats, we take a more reasonable approach, and we wish to inform you of how the medicine has benefited others in the past with this article.

What Is 5-MeO-DMT?

5-MeO-DMT is a psychoactive medicine that has been known to produce a non-dual experience in those who work with it. The corresponding non-dual feeling is precisely what sparks the transformation that the medicine is reputed to ignite. In essence, it allows people to see their lives and the world around them from an entirely novel perspective. Hence, this motivates the individual to pursue their true passions more obstinately, and make changes to live a more fulfilling life.Since the experience is known for its intensity, it's preferable to complete it with the assistance of an experienced guide. If you follow a guide that knows what they're doing, you should have no concerns about safety.5-MeO-DMT compares favorably to other psychoactive drugs such as psilocybin or Ayahuasca. Indeed, the experience is usually far more intense and intellectual, revealing the individual's inner workings of the ego.


So, how did 5-MeO-DMT come to be so popular in the world of psychedelics? 5-MeO-DMT is an ancient medicine with a long history. The first recorded usage that we know of came around 3 millennia ago. Cultures indigenous to South America would find ways to experiment with 5-MeO-DMT that existed in crushed seeds. Contrary to popular belief, 5-MeO-DMT started as a plant medicine and the chemical compound has been identified in 9 different plant species.The next step in the evolution of 5-MeO-DMT came in 1936. 5-MeO-DMT became much easier to distribute and proliferate as two scientists succeeded in synthesizing a synthetic form of the medicine. Thus, it grew in popularity throughout the decades that followed.5-MeO-DMT is most commonly associated with the Bufo Alvarius toad, also known as the Colorado River toad, or the Sonoran Desert toad. However, it was not until the 1980s when toad venom became a common way for people to find 5-MeO-DMT.

Modern Practices

As a result of the popularity of the Bufo Alvarius toad venom, many conservationists have encouraged psychonauts to find more sustainable means of procuring 5-MeO-DMT. For this reason, synthetic and plant sources are considered superior, though all different forms of the medicine provide an equally enlightening experience.Another hurdle for those interested in 5-MeO-DMT has sprung up over the last decade. Several governments around the world followed the lead of the US after they classified it as an illegal substance. It's a great pity, considering how many healing effects 5-MeO-DMT has. Nowadays, one must travel to places like Mexico or Portugal to work with 5-MeO-DMT, where the medicine inhabits a bit of a grey area.

How 5-MeO-DMT Feels

Without question, the 5-MeO-DMT experience differs for everyone. In general, people report that it starts quickly and in a rather unsettling manner. This is the point where having a guide for your trip is crucial because they can help you relax and ultimately surrender to the effects of the medicine.During this time, some people see geometric shapes or fight to maintain control over their bodies. Eventually, you might succumb to the effects of the medicine, and the experience can reach a crescendo, symbolized by a bright white light. This is interpreted as ego death by some. It will seem like a bit of a struggle, but eventually, you'll feel a bright warmth after the fact. You'll attempt to hold onto this feeling as long as you can. However, it will be of no use. Chances are, you'll wake up feeling a lot different than you did before.

How 5-MeO-DMT Works: The Scientific Literature

5-MeO-DMT is a psychoplastogen. Essentially, it is supposed to elevate your neuroplasticity. Consequently, it makes it easier for new pathways to emerge in your brain. The ability to assimilate different perspectives is downstream from this change, hence, the feeling of "ego death".Individuals who work with 5-MeO-DMT usually find it much easier to revise their beliefs about themselves, as embodied by the increase in neuroplasticity. This is highly applicable to mental illness. Researchers at Johns Hopkins University discovered in a 2019 study that around 80% of those they surveyed experienced a self-reported decrease in depression symptoms for months following their work with 5-MeO-DMT. Since the evidence was anecdotal, and limited in scope, it can be difficult to say with certainty that 5-MeO-DMT can improve your mental health. That said, we have great reason to believe that the medicine is helpful.

How 5-MeO-DMT Could Transform Your Life

Now that we have established that there is some reasonable evidence that 5-MeO-DMT is a transformative medicine, we'd like to emphasize some of the ways the transformation could occur.Everyone's journey with 5-MeO is different. Some are looking for a spiritual experience, and others seek to remedy their mental health issues, or at least, an easing of the pain. The only correct path is the one that's true to your needs and values.

The Potential For "Ego Death" And Emotional Rebirth

We've already hinted at ego death. It's an interesting term to use since others would describe their 5-MeO-DMT experience as a rebirth. You might see your entire life in a completely new light as a result of 5-MeO-DMT, and perhaps pursue an entirely different course of action in your relationships, work, and spiritual life. This might prompt a fair few existential considerations, no doubt.

A Better Means Of Interfacing With The World

The ability to see new perspectives can lead you to change your interactions with others. After all, one who might have been too harsh on others might see the effect of their intensity and begin to tone it down. Alternatively, you might not have been assertive enough, and now 5-MeO gives you the confidence to get what you want.We often liken the entire 5-MeO-DMT experience to the hero's journey, a framework that's popular in storytelling across all cultures. To summarize it quickly, a hero will leave home after a call to adventure, then triumph over adversity, and return home as a new and stronger individual. After feeling 5-MeO-DMT, it will be easy to see how easily the two stories correlate.

Treating Mental Illness

We don't take mental health lightly, and we won't promise that 5-MeO-DMT can cure your depression. However, as the anecdotal evidence we discussed earlier suggests, 5-MeO-DMT is instrumental in creating positive mental health outcomes for those who might need them. Of course, the medicine also requires a great deal of inner work for you to feel its full effects.

POST-TRAUMATIC stress disorder

A study in 2020 suggested that 3-5 doses of 5-MeO-DMT administered over 3 days can cause a notable diminishment in symptoms of PTSD. Furthermore, this study observed a sustained enhancement in symptoms of other mental health conditions, including depression and anxiety.


As for anxiety, this study suggested that 5-MeO-DMT helps you feel less anxious starting as early as two hours following your psychedelic trip. Moreover, the anxiety continued to ease in the following days, suggesting that neural pathways are in the process of being formed during this time.


We already discussed the fact that 5-MeO-DMT can play a role in helping alleviate depression. We'd just like to add that no study has been conducted with enough participants over a long enough period for there to be any significant conclusions to be made about 5-MeO-DMT. We eagerly await the legalization of the medicine so that more experimentation can be done.

What 5-MeO-DMT Will Not Do

Given its status as an illegal substance, 5-MeO-DMT has a fair few detractors. These can range from concerns about safety to delusions about the medicine's effectiveness. Let's clear some of these misconceptions up.

Solve All Your Problems For You At Once

Lasting effects of this experience will require your full participation in the integration process.Ultimately, you still have full responsibility for your 5-MeO-DMT experience. While many report feeling a great sense of revelation immediately after their ceremony, this sense of enlightenment will only last if you persistently apply the lessons you learned from the medicine. It will take you months or even years to completely revamp your life. After all, the decisions you make after the fact have consequences that will last well down the road.

Make You Go "Crazy"

It's pretty rare for 5-MeO-DMT to make someone go crazy, and if it does, it means that someone did not vet them properly for their suitability for the medicine. At Tandava Retreats, we always vet our candidates thoroughly, checking for any medications or conditions that might conflict with 5-MeO-DMT. With this measure in place, it's highly unlikely that an unsuitable candidate will slip through the cracks.

Expose You To Unnecessary Risks

The only real way that the 5-MeO-DMT process involves unnecessary risks is if you try to experiment with it by yourself or with someone irresponsible accompanying you. Having a responsible guide to assist you during your trip will work wonders to help alleviate any problems that might arise.As far as long-term risks go, this is one of the most mystifying criticisms that people have of psychedelics. Psychedelic drugs are usually ranked by scientists as some of the least harmful drugs around. Moreover, psychedelics like 5-MeO-DMT are often used to combat addiction like drug and alcohol abuse.

5-MeO-DMT Retreats

Ideally, you'll work with a professional facilitator at a 5-MeO-DMT retreat center to receive the full life-changing benefits of the medicine. Since hosting retreats is our specialty at Tandava, we'll take this opportunity to give you some insight into what such retreats look like from the inside.[caption id="attachment_2019" align="alignnone" width="1024"]

5-MeO-DMT Psychoactive Experience

5-MeO-DMT Experience at Tandava Retreats[/caption]

The Main Components Of The 5-MeO-DMT Retreat

What makes a 5-MeO-DMT retreat so integral to your uptake of the medicine? The answer lies in the preparation you do beforehand and the little details that are taken into consideration during the retreat.

Preparation and Screening

There are two essential components to the pre-screening process. Firstly, we must check whether you have any conditions or take any medications that are contraindicated with 5-MeO-DMT. Furthermore, we want to discuss your reasons for seeking out 5-MeO-DMT to ensure that your heart and mind are in the right place.After we accept your prescreening results, we will have a few more Zoom calls to help you prepare for the retreat. We will get to know you well enough so that you're comfortable with us taking care of you during your 5-MeO-DMT ceremony. Plus, we'll try to tailor the experience to your needs and values so you can make the most of it.Finally, we'll assist you with advice on how you can optimize your experience here before your attendance at the retreat. If you are on any medications that contraindicate with 5-MeO-DMT, we will have you work with your primary care physician to successfully taper off and will be checking in around any potential destabilization.

The Ceremony

Once the day of the 5-MeO-DMT ceremony arrives, it's normal to be nervous. However, since you'll have spent weeks preparing for this moment, you'll do fine. The ceremony itself goes by quickly, usually taking around 10 to 45 minutes. However, it will seem to last much longer while you're under the influence of the medicine.During the ceremony, you'll lie on a flat mat with your head resting on a pillow, and our two facilitators will sit by your side burning incense and singing chants. We will do everything to ensure that your experience is comfortable. They have first aid experience to intervene in the case of any emergency.

The Activities

One of the integral parts of our retreats is that they also offer the opportunity for contemplation and relaxation. After all, you're likely going to contend with very heavy subjects. To allow you to focus your full energy on that, the rest is meant to be relaxing.Therefore, we begin every day at our retreat center with some breathwork, meditation, and yoga. We believe this puts you in the perfect state to be receptive to new insights. You can track your brain activity before and after your 5-MeO-DMT trip with our neurofeedback devices, which show you the degree of mental patterning that's occurring.Aside from this, there should be ample opportunity for relaxation at a retreat. We take care of all our guests' meals. Not to mention, we offer a sauna, a swimming pool, and various hiking adventures to help you unwind.

Post-retreat Integration

The final, and possibly most significant, portion of your 5-MeO-DMT experience will take place following the retreat. We mentioned earlier that for you to benefit from 5-MeO-DMT to the fullest extent, you must perform a great deal of inner work. Well, integration is the name we give to that assimilation process.Some psychonauts make the mistake of jumping from one experience to the next in hopes of finding a better answer to their inner battles. Let's face it, these people are likely just trying to avoid the challenging inner work that is required for you to realize your potential after one of these sessions.We won't sugar coat it, 5-MeO-DMT might require you to face your biggest fears. However, you'll usually do so with a peaceful disposition. Moreover, you'll have the full support of the facilitators that help you complete the integration process.Naturally, integration must align with your personal goals. That's why we spend so much time getting to know you before the retreat starts. It's the only way for us to give you adequate assistance in dealing with your struggles.Here's an example of how 5-MeO-DMT can help in this regard. Let's say you have some sort of addiction. That addiction might have been the result of some past trauma and now you are using the addiction to cope. 5-MeO-DMT could help unweave all the negative mental patterning that led you to this point. As a result, you'll be able to easily identify the moments when your addictive behaviour is about to spiral out of control and nip those behaviours in the bud.The process of integration is there to help you stick to your goals. 5-MeO-DMT might have revealed the path to a better place, but you'll need significant moderation to get there. That's why we say that the 5-MeO-DMT ceremony is only the first step.

5 Stories About 5-MeO-DMT That Will Show You Its Potential

To keep these stories anonymous, we'll highlight the experience rather than the individual. After reading these, you'll understand the kind of power that 5-MeO-DMT has in bringing clarity to inner conflicts.

Growing More Comfortable

"I was, prior to the retreat, terrified at the prospect of spending a few days around complete strangers. This was my challenge, I never felt I could be myself around others.Fortunately, the medicine helped me see that everyone has intense emotions and that it is understandable for me to feel them too. Instead of denying my feelings, I've come to accept them and grow comfortable around them. Thus, I feel more comfortable socializing and sharing my thoughts and feelings with others."

Newfound Self-love

"I've been searching for love my whole life, but I never realized that I could find it within. Finally, I can love myself and I can forgive myself for the things I've done wrong in the past. I'm so grateful to the medicine for showing me this.The medicine really is like a rebirth. I realized that my perceptions completely changed when I woke up from the trip. Anybody looking to make huge changes in their life should at least consider what 5-MeO-DMT can do."

Inner Peace

"Before working with 5-MeO-DMT, I would not have been able to imagine the profound effect this medicine has had on my being. I've had a great deal of trauma recently, however, my soul now feels that it has an answer to some of the terrifying questions I was asking myself. I now have the love and support I need to effectively cope with my son's passing."

Being More Open

"I think we all have limiting beliefs, but those beliefs nagged at me incessantly all day long. I was always a very nervous person. That's until I went on this retreat.I'm now endowed with an amazing sense of liberty. I literally feel the power to conquer the world building up inside of me. Of course, that's not my intention. But I'm free to pursue my goals without any hindrance. If you think about it, fear is like a compass, and it always points you in the wrong direction. 5-MeO-DMT has allowed me to change the compass' polarity and make it point to my true desires rather than my inner fears."

Battling My Demons

"After experiencing this retreat, I can firmly say that I have found no better medicine in 39 years to heal from my past conflicts. The oneness that you feel when you're in the 5-MeO-DMT ceremony is incredible. It seems to me that we're all connected, every animal, every plant, it's all us, it's all the universe. It's incredible how much my perspective has shifted in such a small timeframe."

Discover What's Possible With Tandava

If you're intrigued by the possibilities that this medicine offers, we encourage you to explore more by contacting us to ask any questions you have about the medicine and its impacts. Embarking on a 5-MeO-DMT retreat is a big step, so we don't ask you for any commitment right away. The important thing to us is that you fully understand what the medicine does and doesn't do.